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Melatonin and Heart Failure: Separating Fact from Fiction

11/9/2025
Recent study raises concerns about melatonin's link to heart failure, but experts urge caution. Learn what the research really says about this popular sleep aid and its safety.
Melatonin and Heart Failure: Separating Fact from Fiction
Don't panic over new melatonin studies! Experts clarify risks and recommend discussing sleep aids with your doctor for safe use.

The Truth About Melatonin and Heart Failure: What You Need to Know

Recent headlines have sparked concern regarding the sleep supplement melatonin and its potential link to heart failure. However, experts urge caution and a measured response to these preliminary reports. The message is clear: don’t lose sleep over the headlines. While the study raises questions about the long-term safety of melatonin for treating insomnia, it’s essential to understand the context and limitations of the research.

Understanding the Study

Doctors have long recognized that insufficient sleep can elevate the risk of heart disease. However, heart specialists emphasize that the observational nature of this study does not establish a direct cause-and-effect relationship between melatonin usage and heart failure. Dr. Pratik Sandesara, an interventional cardiologist at Emory Healthcare, who was not involved in the study, stated, “We should not raise the alarm and tell patients to stop taking all their melatonin.”

How Melatonin Works

Melatonin is a natural hormone produced by our bodies that regulates sleep cycles. Typically, melatonin levels rise in the evening as darkness sets in, promoting drowsiness. Many individuals choose to take lab-produced melatonin supplements to assist with falling asleep, particularly when dealing with jet lag or adjusting to time changes.

Study Findings and Implications

The recent study, which utilized international electronic health records, tracked adults diagnosed with insomnia who had been prescribed melatonin for at least one year. Over a five-year period, the findings revealed that 4.6% of chronic melatonin users developed heart failure, in contrast to 2.7% of insomnia patients who did not use melatonin. It’s important to note that this study, presented at an American Heart Association meeting, has not yet undergone peer review, which raises questions about its findings.

Prescription vs. Over-the-Counter Use

Another critical aspect to consider is that melatonin is available over-the-counter in the United States, meaning that many Americans might have used the supplement without any formal prescription. Dr. Clyde Yancy, chief of cardiology at Northwestern University and not affiliated with the study, pointed out that the research does not account for the dosages of melatonin used. Additionally, U.S. supplements are not regulated by the government, resulting in variations in ingredient quality among different brands.

The Call for Further Research

The researchers from SUNY Downstate Health Sciences University characterized their findings as a prompt for additional research into the long-term effects of melatonin. Until more definitive conclusions are reached, patients should consult their doctors when considering melatonin supplementation. According to Dr. Sandesara, melatonin is generally recommended for short-term use, particularly for conditions like jet lag.

Practicing Good Sleep Hygiene

While the study does not confirm that long-term melatonin use poses a danger, it also fails to provide evidence supporting indefinite use. Dr. Yancy emphasized that improving sleep hygiene is vital for achieving better sleep quality. This includes ensuring that your sleeping environment is dark, as exposure to blue light at night can suppress melatonin production—a critical factor for restful sleep.

Conclusion

In summary, while the recent study raises important questions about melatonin use and heart health, it is crucial not to overreact. Patients are encouraged to have open conversations with their healthcare providers regarding the use of melatonin and to practice good sleep hygiene for overall well-being. Remember, sleep problems are not just about feeling tired; they can significantly impact your health.

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