A remarkable transformation story has emerged from Hannah Mai, a 37-year-old woman from Coventry, Warwickshire, who successfully lost 10 stone (approximately 6.3 kg) after being diagnosed with the rare hormonal disorder known as Cushing's disease. Her journey, which took place over the span of just two years, highlights the power of dedication and the effectiveness of daily exercise—specifically, pilates. Hannah achieved her weight loss without the aid of popular weight-loss medications like Ozempic.
In October 2020, Hannah's life changed dramatically when she was diagnosed with Cushing's disease, a condition characterized by prolonged exposure to high levels of cortisol. This hormonal imbalance often leads to significant symptoms such as weight gain around the abdomen, upper back, and a round face—commonly referred to as a 'moon face.' Notably, this condition has recently garnered attention after comedian Amy Schumer revealed her own diagnosis in early 2024.
Hannah first noticed her weight spiraling out of control at the age of 30, experiencing a staggering gain of seven stone within a few months. Despite multiple trips to her doctor expressing concern, Hannah was often met with assumptions about pregnancy or hormonal changes. She recounted, "I knew there was something wrong with me, but people around me thought I had changed my diet." Over time, her weight peaked at 20 stone (approximately 127 kg), prompting her to take action.
In October 2022, after waking up with a hunched back, Hannah took to Google to research her symptoms. This led her to discover Cushing's disease, which prompted her to return to her doctor equipped with information on her condition. Following a blood test and MRI scan at University Hospital Coventry and Warwickshire, Hannah received the diagnosis she had long suspected.
Hannah underwent brain surgery in February 2021 to remove the pituitary tumor responsible for her condition. This benign tumor is the most common cause of spontaneous Cushing's, accounting for approximately 70% of cases, according to The Pituitary Foundation. Post-surgery, she was prescribed steroid medication to manage her condition, which complicated her weight loss efforts.
After two years on steroids, Hannah was taken off the medication and became determined to reclaim her health. Weighing 20 stone 5 lbs (about 129 kg) and wearing a size 26 dress, she adopted a new lifestyle that focused on a high-protein diet and daily pilates workouts. "I cut out all sugar, dairy, and gluten after being diagnosed with celiac disease," she explained. "Now, I follow a low-carb, high-protein diet filled with vegetables." This commitment helped her to lose weight, ultimately bringing her down to 10 stone 4 lbs (approximately 65 kg).
Today, Hannah has successfully reduced her dress size from 26 to 10, returning to the size she wore before her diagnosis. She expressed immense pride in her journey, stating, "I feel so much happier. When I look back at myself, I just can't believe I was that size." In addition to her personal triumph, Hannah is now actively raising funds for The Pituitary Foundation, an organization dedicated to supporting those affected by pituitary disorders.
Regarding the rising popularity of medications like Ozempic, which are often used off-label for weight loss, Hannah commented, "I think Ozempic is great for people who need it, and for medical reasons. It is really helping some people, but I feel if you give yourself a chance, you can really push yourself." Her perspective emphasizes the importance of personal determination and the belief that sustainable weight loss is achievable through hard work and commitment.
Hannah's story not only showcases her incredible weight loss journey but also highlights the necessity for awareness regarding Cushing's disease and its symptoms. Her experience sheds light on the challenges faced by those dealing with hormonal disorders and inspires others to take charge of their health. As she reflects on her past, Hannah encourages others to recognize their potential and strive for their health goals, regardless of the obstacles they may face.
