In recent years, the use of anti-Type 2 diabetes medications such as Mounjaro and Ozempic has surged among celebrities seeking weight loss solutions. Notably, comedian Rosie showcased her dramatic transformation on Instagram in May 2025 after being on Mounjaro since late 2022. She expressed disbelief at her new appearance, posting, “I can’t believe this is me now,” accompanied by hashtags like mounjaro, weightloss, and bodydysmorphia.
Following the birth of their first child in 2021, singer Meghan Trainor and her husband Daryl Sabara took on the 75 Hard challenge as a couple. In a recent episode of their podcast, *Workin’ On It*, Meghan detailed how they noticed many friends and even their doctors were using Mounjaro and Ozempic. They decided to start on the lowest dose available, combining the medication with regular exercise and a balanced diet. “Daryl and I both do everything together,” Meghan explained, highlighting their joint commitment to health.
Former *Girls Next Door* star Kendra Wilkinson shared her own experience with weight loss injections. In April 2025, she revealed on Instagram that she had tried one unnamed weight loss injectable but quickly abandoned it after just one dose. “I heard too many horror stories around me,” she explained, expressing concern over potential health risks associated with these medications.
Moreover, during an appearance on *The Tonight Show Starring Jimmy Fallon* in March 2025, a well-known Golden Globes host defended Ozempic, advocating for more openness about its use. “I love it. I’m like, ‘Do it,’” she remarked, emphasizing the need to eliminate stigma surrounding the medication. She argued that the judgment often comes from those who are naturally thin, who might feel threatened by others achieving their health goals.
Several celebrities have reported adverse reactions to Ozempic. For instance, in December 2024, model Nader discussed how the medication made her nauseous, leading her to stop taking it when she began competing on *Dancing With the Stars*. Similarly, Dog the Bounty Hunter's daughter revealed that she lost 58 pounds over ten months by changing her diet and using Tirzepatide, but had previously had a negative experience with Ozempic.
Kate Moss’ sister also shared a harrowing account of her experience with Ozempic, describing it as the worst decision she ever made. After taking a high dosage, she experienced severe dehydration and even had to be hospitalized due to a seizure. Her story underscores the potential dangers associated with weight loss medications.
In a candid interview, actress Kate Winslet admitted she was unaware of what Ozempic was until recently, expressing concern over the weight loss trend. She emphasized the importance of sustainable weight loss methods. Meanwhile, *The Hills* star Heidi Montag specified her commitment to healthy living, stating, “There are no shortcuts in life,” and rejecting the notion of using medications like Ozempic for weight loss.
Moreover, comedian Amy Schumer openly criticized celebrities who misrepresent their weight loss journeys, emphasizing the importance of honesty. She shared her own struggles with Ozempic, noting that it hindered her ability to engage with her child due to the side effects.
As the popularity of Ozempic and Mounjaro continues to rise, so does the public discourse surrounding their use. In an April 2023 Instagram post, actress Sophie Turner expressed her frustration with advertisements promoting these medications for weight loss, emphasizing the need for a more responsible approach. The manufacturer of Ozempic, Novo Nordisk, has stated that the drug is not FDA-approved for chronic weight management, highlighting the importance of using such medications under medical supervision.
In conclusion, the use of weight loss medications like Mounjaro and Ozempic has become a hot topic among celebrities and the public alike. While some individuals have reported success, many have also shared cautionary tales about the potential side effects and health risks. As this trend unfolds, it is crucial for users to remain informed and consult healthcare professionals before embarking on any weight loss journey.
