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Week 2 NFL Predictions: Can the Commanders Upset the Packers?

9/11/2025
As Week 2 of the NFL season approaches, predictions are heating up! Will the Packers maintain their momentum against the Commanders? Find out what experts are forecasting for all the exciting matchups this week!
Week 2 NFL Predictions: Can the Commanders Upset the Packers?
Get the latest predictions for Week 2 of the NFL! Can the underdogs pull off an upset? Read for expert insights!

Stop the fight! In Week 1 of the NFL season, Chris Simms and I disagreed on seven of the 16 games. Remarkably, I went 7-0 in those disagreements. As we gear up for Week 2, we find ourselves at odds on five games, which could either extend my lead to an impressive 12 wins or narrow it down to just two. In Week 1, I achieved a record of 13-3 straight up and 9-7 against the spread, while Simms struggled with a 6-10 record and went 3-13 against the spread. For all your Week 2 picks, you know what to do!

Game Previews and Predictions for Week 2

Commanders at Packers (-3.5)

The Green Bay Packers appear to be a team of destiny this season. However, the Washington Commanders have a golden opportunity to thwart their ambitions. In my prediction, I see the Packers winning decisively with a score of 27-17. Simms, on the other hand, believes the game will be closer, predicting a 28-24 victory for the Packers.

Browns at Ravens (-11.5)

Last year, the Baltimore Ravens came out flat in Week 2 following a close playoff rematch loss in Week 1. This time around, they are prepared to make a statement. I predict a commanding win for the Ravens, 30-14. Simms has a similar outlook, picking the Ravens to win 31-20 against the Cleveland Browns.

Jaguars at Bengals (-3.5)

The Cincinnati Bengals have shown noticeable improvement in their defense, but their offense still needs to find its rhythm quickly. My prediction leans towards a close game, with the Bengals edging out the Jaguars 24-20. Simms, however, believes the Jacksonville Jaguars will pull off an upset with a 27-23 victory.

Giants at Cowboys (-4.5)

This matchup used to be a prime time spectacle, drawing attention from every network. I believe the Dallas Cowboys will take control, predicting a score of 23-13 in their favor. Simms echoes this sentiment, projecting a 28-17 victory for the Cowboys over the New York Giants.

Bears at Lions (-6)

The Detroit Lions are experiencing some growing pains this season after a stellar 15-2 record in 2024. They are still learning how to win consistently. I predict the Lions will win a competitive game against the Chicago Bears with a score of 27-23, while Simms sees it ending 24-17 in favor of the Lions.

Patriots at Dolphins (-1.5)

The Miami Dolphins face a critical moment in their season; losing this game could set them back significantly. I predict the Dolphins will narrowly defeat the New England Patriots with a score of 24-21. However, Simms thinks the Patriots will surprise everyone and win 20-17.

49ers (-3) at Saints

In a matchup that many are keen to watch, Kyle Shanahan's San Francisco 49ers will face the New Orleans Saints. Four years after a contentious draft decision, both teams will be looking to secure a win. I predict a close game, with the 49ers winning 17-13. Simms has a slightly higher score, predicting a 20-16 victory for the 49ers.

Bills (-6.5) at Jets

The Buffalo Bills have shown their strength early in the season. Despite the New York Jets showing some improvement, I foresee the Bills winning this game decisively, 34-21. Simms also believes in the Bills but predicts a closer 31-27 score.

Seahawks at Steelers (-3)

With Aaron Rodgers making his home opener for the Pittsburgh Steelers and coming off a stellar performance last week, I believe the Steelers will come out on top, winning 24-13 against the Seattle Seahawks. Simms agrees with a similar prediction of 20-13.

Rams (-5.5) at Titans

The Tennessee Titans have potential but are not quite ready to tackle playoff-caliber teams. I predict the Los Angeles Rams will win this matchup 17-13, while Simms thinks the Rams will secure a 20-13 victory as well.

Panthers at Cardinals (-6.5)

Despite the Carolina Panthers not being consistently blown out last season, I believe they will struggle against the Arizona Cardinals. I predict a score of 21-13 in favor of the Cardinals, while Simms sees it being a bit closer at 21-17.

Broncos (-1.5) at Colts

The Indianapolis Colts may just be the real deal this season. I predict they will pull off an upset against the Denver Broncos, winning 23-20. Simms, however, believes the Broncos will prevail with a score of 27-24.

Eagles (-1.5) at Chiefs

In what promises to be an exciting matchup, I believe the Philadelphia Eagles will edge out the Kansas City Chiefs with a score of 27-24. Simms, more confident in the Eagles, predicts a 31-21 victory.

Falcons at Vikings (-3.5)

With Brian Flores showing strong defensive strategies against young quarterbacks, I expect the Minnesota Vikings to take this win over the Atlanta Falcons with a score of 30-21. Simms, however, sees a much tighter game ending 19-17 in favor of the Vikings.

Buccaneers at Texans (-2.5)

This matchup is a true coin flip. An interesting factor is Baker Mayfield returning to his home state of Texas. I predict a close win for the Buccaneers, 24-23, while Simms believes the Texans will take it 20-17.

Chargers (-3) at Raiders

The Las Vegas Raiders have exceeded expectations this season, but the Los Angeles Chargers are also proving to be formidable. I predict a solid performance from the Chargers, winning 27-20, and Simms concurs with the same score.

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