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Top Waiver Wire Picks for Week 6: Who to Add and Who to Drop

10/7/2025
As injuries and bye weeks shake up fantasy rosters, discover the key players to add from the waiver wire for Week 6. From quarterbacks to tight ends, ensure your lineup stays competitive with these essential additions!
Top Waiver Wire Picks for Week 6: Who to Add and Who to Drop
Injuries and bye weeks are wreaking havoc! Check out our top waiver wire picks for Week 6 and ensure your fantasy lineup is ready to compete.

In last week's waiver wire column, several players made significant impacts during Week 5, leading to numerous victories for Fantasy football managers. Notable performances included Sam Darnold, who emerged as a top-three quarterback, and Rico Dowdle, who claimed the title of the No. 2 running back. Additionally, tight ends Theo Johnson and Darren Waller both ranked among the top five at their position. Now, as we head into Week 6, it’s time to explore some plug-and-play options available on the waiver wire to bolster your Fantasy roster.

Injury Monitoring and Bye Weeks

In Week 6, only two teams will be on a bye: the Minnesota Vikings and the Houston Texans. However, several injuries are worth monitoring, particularly that of Omarion Hampton, who has been placed on injured reserve due to an ankle injury. With Hampton sidelined, the backfield will likely consist of a tandem featuring Kimani Vidal and Hassan Haskins, which could present challenges. Additionally, keep an eye on Kenneth Gainwell, who is expected to be the top running back to add this week, while also checking the availability of Michael Carter, who could be a valuable addition.

Top Running Back Additions

This week, several running backs stand out as must-adds. Aside from Gainwell, Kendre Miller, Tyrone Tracy Jr., and Tyjae Spears also present solid options. Dowdle, who had a stellar game against the Dolphins in Week 5, scoring an impressive 32.4 PPR points, should be a top priority if Chuba Hubbard is unable to play. As for Carter, he performed well in his starting role for the Cardinals, and he should be a reliable low-end No. 2 running back against the Colts.

Wide Receiver Targets

When it comes to wide receivers, Kendrick Bourne is the standout addition this week, particularly if Ricky Pearsall and Jauan Jennings remain sidelined. Other receivers worth considering include Tre Tucker, Rashid Shaheed, and Jalen Coker, who is anticipated to make his 2025 debut in Week 6. Darnold tops the list of quarterbacks to add this week, but keep an eye on Tua Tagovailoa and Mac Jones, who could also see significant playtime.

Top Tight Ends to Consider

For tight ends, the best options to add include Mason Taylor, A.J. Barner, Theo Johnson, and Jake Tonges, all of whom delivered strong performances in Week 5. As injuries and bye weeks continue to impact rosters, the waiver wire provides a timely opportunity to strengthen your lineup.

Quarterback Waiver Wire Recommendations

This week, notable quarterbacks on a bye include C.J. Stroud, Carson Wentz, and J.J. McCarthy. Pay attention to the injury reports for Lamar Jackson, Brock Purdy, and Joe Burrow. Stroud, who is currently 70 percent rostered, has been performing well, making him a valuable asset post-bye. If you’re in a one-quarterback league, it might be time to drop Geno Smith, who has struggled significantly in recent games.

Running Back Analysis

Several running backs stand out this week, with key players on a bye including Jordan Mason, Aaron Jones, and Nick Chubb. Dowdle, Bhayshul Tuten, and Michael Carter are all strong additions. Dowdle’s remarkable performance against the Dolphins makes him a must-add if Hubbard is unavailable. Meanwhile, Carter’s consistent performance as the Cardinals' starter against the Colts makes him a worthwhile low-end No. 2 running back.

Wide Receiver Insights

With several key wide receivers on a bye, including Justin Jefferson and Nico Collins, now is the time to target players like Wan'Dale Robinson, Cooper Kupp, and Matthew Golden. Robinson has shown promise as the top receiver for the Giants, while Kupp remains a valuable stash in PPR leagues. Golden’s recent performances suggest he could develop into a solid No. 3 Fantasy receiver.

Tight End Recommendations

For tight ends, David Njoku and Kyle Pitts are worth adding this week. Njoku has recently had a standout performance, while Pitts appears to be finding his rhythm. Both players should be available in shallow leagues and could provide valuable depth as we move through the season.

Streaming Options for DST and Kickers

As we navigate through the chaos of injuries and bye weeks, consider streaming options for defense and kickers to maximize your roster's potential. Recommended streaming defenses include the Patriots against the Saints, Raiders facing the Titans, and the Titans at the Raiders. For kickers, look for viable options that can provide a boost to your scoring potential.

It's crucial to stay proactive on the waiver wire as we approach Week 6. With injuries and bye weeks affecting many Fantasy rosters, the right additions from the waiver wire can make all the difference in your team's success this season.

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