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Seahawks vs. Cardinals: Expert Score Predictions for Week 4 Clash

9/24/2025
As the Seahawks prepare to face the Cardinals in Week 4, experts weigh in with their predictions. Will Seattle's defense shine, or will Kyler Murray's agility lead Arizona to victory? Check out the insights!
Seahawks vs. Cardinals: Expert Score Predictions for Week 4 Clash
Get the latest score predictions for the Seahawks vs. Cardinals Week 4 matchup. Experts discuss key factors and potential outcomes in this thrilling NFL encounter.

Score Predictions for Seahawks vs. Cardinals in Week 4

The highly anticipated Week 4 matchup between the Seattle Seahawks and the Arizona Cardinals is generating plenty of buzz, and predictions are rolling in from sports analysts. This game, set in Glendale, Arizona, promises to be an exciting showdown as both teams look to solidify their positions in the NFC West. Below are the predictions from The Seattle Times sports staff, each providing their unique take on how the game will unfold.

Matt Calkins' Prediction: Cardinals 21, Seahawks 20

Matt Calkins, with a record of 2-1 in predictions, foresees a nail-biting game with the Cardinals edging out the Seahawks by a single point. He emphasizes that while Seattle’s defense has been impressive, the elusiveness of Kyler Murray will likely prove decisive. Calkins suggests that the Seahawks' offense may struggle to find its rhythm, ultimately leading to a close victory for Arizona.

Tim Booth's Prediction: Seahawks 25, Cardinals 18

Tim Booth, also at 2-1, predicts a slightly more favorable outcome for the Seahawks. He notes the peculiar nature of games in Arizona and hints at the possibility of a rare NFL score combination. With the Cardinals reeling from the loss of James Connor and a recent defeat in San Francisco, Booth believes the Seahawks, having rested their starters against the Saints, will capitalize on their fresh legs to secure a win in the desert.

Mike Vorel's Prediction: Seahawks 24, Cardinals 20

Mike Vorel, currently at 1-2 in predictions, is optimistic about the Seahawks pulling off a victory. He recalls last year's performance where Seattle's running game thrived with Zach Charbonnet leading the charge. However, he notes that the Cardinals boast a formidable rushing defense, currently ranked fourth in the league. Despite this, Vorel believes that Sam Darnold and the Seattle defense are up to the challenge and will help the team secure its eighth consecutive road win.

Bob Condotta's Prediction: Seahawks 23, Cardinals 13

Bob Condotta, with a prediction record of 1-2, sees the Seahawks winning comfortably against the Cardinals. He points out that while both teams have similar records at 2-1, Arizona's recent performances have lacked depth. Condotta highlights the significant impact of James Conner's injury on Arizona's offense, suggesting that the Seahawks will leverage their strong defensive capabilities to secure another victory in Glendale.

Review of Previous Weeks

The Seattle Seahawks have shown impressive form leading to this matchup, including a dominant performance against the New Orleans Saints in Week 3, where they won 44-13. Analysts’ predictions for this game included:

Calkins: Seahawks 28, Saints 17Booth: Seahawks 27, Saints 12Vorel: Seahawks 27, Saints 17Condotta: Seahawks 27, Saints 13

In Week 2, the Seahawks defeated the Pittsburgh Steelers 31-17, with predictions being:

Calkins: Steelers 28, Seahawks 21Vorel: Steelers 24, Seahawks 20Condotta: Steelers 21, Seahawks 16Booth: Seahawks 18, Steelers 17*

Finally, in the opening week, the Seahawks narrowly defeated the San Francisco 49ers 17-13, with predictions as follows:

Condotta: Seahawks 23, 49ers 17Vorel: Seahawks 24, 49ers 20Calkins: 49ers 20, Seahawks 17*Booth: Seahawks 23, 49ers 17

As the Seahawks prepare for this crucial game against the Cardinals, fans are eager to see if the team's recent momentum will carry them through to another victory on the road.

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