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Fantasy Football Insights: Top Running Backs and Matchup Analysis for Week 10

11/7/2025
Dive into our detailed analysis of running backs for Week 10, exploring projected points, matchups, and must-start players. Get ahead in your fantasy league with our expert insights!
Fantasy Football Insights: Top Running Backs and Matchup Analysis for Week 10
Discover the best running backs to start in your fantasy lineup this week with expert analysis and matchup insights for Week 10.

Week 9 Fantasy Football RB and WR Analysis

This week, several running backs and wide receivers are poised to make significant impacts in fantasy football. Understanding player usage, projected points, and matchup details is crucial for making informed lineup decisions. Below is a comprehensive analysis of the top performers and their potential this week.

Colts and Jonathan Taylor's Strong Position

Jonathan Taylor is currently ranked as the RB1 based on usage metrics this month, and the Indianapolis Colts are projected to score 27.5 points in their upcoming matchup. While there is a slight concern regarding Taylor's involvement in passing situations—given the Colts' pass-heavy tendencies in neutral and negative game scripts—his consistent involvement in the pass game mitigates those worries. Taylor remains a strong start this week.

Falcons and 49ers Matchup Insights

The Atlanta Falcons face the San Francisco 49ers, who are 13th in projected points this week at 22.75. However, the Rams have proven tough against running backs, allowing just 12.7 fantasy points per game—the lowest in the NFL. Christian McCaffrey stands as the RB2 based on usage this month, making him a valuable fantasy asset despite the tough matchup.

Chicago Bears' Running Game

The Chicago Bears are showing potential with Monangai, especially after D'Andre Swift was sidelined last week due to a groin injury. Monangai recorded a season-high 25.6 expected half PPR points last week with nearly 200 total yards. The Bears are projected for 25.5 points against the New York Giants, who have struggled against fantasy running backs, making Monangai a viable starter this week.

Panthers' Dowdle Shines Without Hubbard

Rico Dowdle had a strong performance last week, accumulating 20.2 expected half PPR points against the Green Bay Packers. With Chuba Hubbard benched, Dowdle is expected to carry the load against the New Orleans Saints, who have allowed an average of 158 rushing yards per game to opposing RBs over the past three weeks. Dowdle remains a must-start this week.

Running Back Insights: Achane and Cook

De'Von Achane has emerged as an essential part of the Miami Dolphins' offense, particularly in the absence of Tyreek Hill. He averages 18.5 half PPR points across four games without Hill, making him a strong consideration against a Buffalo Bills defense that struggles against RBs. Meanwhile, James Cook is also making waves, ranking as the RB5 based on usage this month. The Bills are projected to score 30.0 points, which boosts Cook's fantasy outlook.

Wide Receiver Highlights

This week, Jordan Addison is expected to play a crucial role for the Minnesota Vikings against the Baltimore Ravens. He’s the WR21 on WR25 usage this month, and with the Vikings projected for 22 points, he could see an uptick in targets, especially in a favorable matchup. Rashid Shaheed is another player to watch, projected to thrive in a favorable matchup with the Buccaneers, who are 3rd-best against fantasy WRs.

Seahawks' Offensive Strategy

The Seattle Seahawks are projected for 25.75 points against the Arizona Cardinals. Ken Walker has shown promise, particularly in red-zone situations, making him a solid FLEX option. His involvement in the passing game could also increase, allowing for more opportunities to score points.

Injury Updates and Impacts

Injuries are always a concern in fantasy football. Bucky Irving did not practice this week, impacting the Bucs' rotation. Amon-Ra St. Brown remains a question mark as well, with the Lions expected to score 29.5 points against a weakened Commanders defense. Keep an eye on injury reports as they can drastically change player values leading up to game time.

Conclusion

This week presents various opportunities for fantasy football managers to capitalize on player usage and matchups. Staying updated on injuries and projected points will be essential for setting your lineup. Key players like Jonathan Taylor, Christian McCaffrey, and Rico Dowdle should be prominently featured in your strategies, while emerging talents like Jordan Addison and Rashid Shaheed can provide significant upside. Good luck with your matchups this week!

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