The 95th edition of the All-Star Game is set to showcase the fierce rivalry between the American League and the National League on Tuesday night. Last year, the American League triumphed over the National League with a score of 5-3, continuing a dominant streak in this annual exhibition. In fact, the AL has managed to secure victory in nine of the last ten All-Star games, cementing their lead in the all-time series at 48-44.
For this exciting matchup, Paul Skenes will take the mound for the National League, while Tarik Skubal will represent the American League. Fans can catch the first pitch live from Truist Park in Atlanta, scheduled for 8 p.m. ET. Since 1997, the American League has dominated with an impressive record of 22 wins, 4 losses, and 1 tie in the All-Star Game.
According to the latest 2025 MLB All-Star Game odds from DraftKings Sportsbook, the National League is favored at -132 on the money line, meaning a risk of $132 would yield $100 in profit. Meanwhile, the American League stands at +108. Additionally, the over/under for total runs scored is set at 7, indicating how the sportsbooks expect the game to unfold.
Before placing any 2025 MLB All-Star Game picks or making predictions, it's crucial to consider the insights from expert analyst Bruce Marshall at SportsLine. A well-known figure in the sports betting community, Marshall has appeared on numerous sports talk shows and has contributed to prominent publications such as the Las Vegas Review-Journal and the New York Post. With a track record of winning various handicapping titles, he is currently delivering exceptional results for SportsLine members, boasting a remarkable return of +1022 on his last 92 MLB picks.
As the All-Star break approaches, Marshall is leaning towards the under on the run total for this game. He has identified a critical x-factor that could make one side the value pick, providing valuable insight for anyone looking to make informed bets on this highly anticipated event.
