Prince Frederik of Luxembourg, the beloved son of Prince Robert of Luxembourg and Princess Julie of Nassau, has sadly passed away at the young age of 22. The announcement was made by Prince Robert through a heartfelt statement on the official website of the POLG Foundation, an organization that Frederik established to support research and treatments for PolG mitochondrial disease, a rare genetic disorder he battled since birth. Prince Robert revealed that Frederik died on March 1, leaving the family and those who knew him devastated.
In a poignant reflection shared the day before his passing, which coincidentally fell on Rare Disease Day, Prince Robert recounted how Frederik spent his last moments surrounded by family. He spoke with his brother Alexander, sister Charlotte, cousins, and other extended family members, sharing heartfelt farewells that were filled with his unique brand of humor. "Even in his last moments, his humor, and his boundless compassion, compelled him to leave us with one last laugh," Prince Robert wrote.
Frederik’s final words to his father, “Papa, are you proud of me?” carried a profound weight. After days of limited speech, these words were a surprising yet deeply meaningful expression of his need for affirmation regarding his life’s contributions. His father assured him, “The answer was very easy,” expressing pride in Frederik’s remarkable spirit and achievements.
In his tribute, Prince Robert described Frederik as a true superhero, not only to his family but also to countless friends and supporters around the world. "Frederik knows that he is my Superhero, as he is to all of our family," he stated, emphasizing the impact Frederik had through the POLG Foundation. This foundation was born from Frederik's determination to inspire and lead by example, especially as he faced the challenges of PolG mitochondrial disease.
PolG mitochondrial disease is a complex genetic disorder that affects the body’s cells, robbing them of energy and leading to progressive dysfunction across multiple organ systems, including the brain, nerves, liver, intestines, and muscles. Diagnosed at the age of 14, Frederik's journey with this illness was marked by a lack of effective treatment options. The disease is notoriously difficult to diagnose due to its wide range of symptoms and effects.
Prince Robert explained that Frederik didn't want this devastating disease to define him, yet he embraced the mission of the POLG Foundation wholeheartedly. Frederik played a pivotal role in shaping the foundation's objectives and even launched a clothing line called MITO, with encouragement from fashion designer Donna Karan. He also dedicated himself to research, developing mouse models and cell lines in Switzerland, the United States, and Europe to facilitate advancements in understanding and combating PolG disease.
Frederik's passionate commitment to finding a cure for PolG mitochondrial disease has left a lasting legacy that will continue to inspire efforts in the medical community. Through the POLG Foundation, he aimed to raise awareness and support for those affected by this rare condition. His compassion and drive to make a difference in the world serve as a reminder of the profound impact one individual can have, even in the face of overwhelming challenges.
As we remember Prince Frederik, we honor his spirit and the contributions he made during his brief but impactful life. His legacy will undoubtedly continue to inspire and uplift many, ensuring that his efforts in the fight against PolG mitochondrial disease will not be forgotten.
